IUI is a fertility treatment that involves placing sperm inside a woman’s uterus to facilitate fertilization. Sperm that have been washed and concentrated are placed directly in the uterus around the time of ovulation. Depending on the reasons for infertility, IUI can be coordinated with normal cycle or with fertility medications. The success rate of the procedure is reported to be 10-15%, and the cumulative success rate increases with repetition.
Indications of IUI
IUI is used in couples who have one or more of the followings :
- Unexplained infertility
- Mild male factor infertility
- Cervical factor infertility
- Minor cases of endometriosis
- Sexual dysfunction (difficult or impossible to engage in normal sexual intercourse)
- Failed timed-intercourse
Procedure of IUI
Natural IUI or Stimulated IUI
“Natural IUI” is performed when the patient’s menstrual cycle is regular and she does not want multiple pregnancy.
“Stimulated IUI” is performed with fertility medications to induce ovaries to release multiple oocytes, as described above.
Semen samples are collected through masturbation, and then sperms with high motility are separated after being treated with a special medium to enhance the likelihood of in vivo fertilization.
With hCG injection, insemination is timed as closely to ovulation as possible. The insemination is accomplished by inserting a small, sterile catheter containing the sperm into the uterine cavity.
The embryo gets implanted in the uterus 5 to 7 days after IUI.. After 10 to 11 days of IUI procedure, blood test is performed to check for conception.