Causes and Treatment of Habitual Abortion

Chromosomal Abnormality

Chromosomal abnormality can occur in the fetus if one of the parents (or both) has a chromosomal abnormality. This can lead to recurrent miscarriagesy. About 6% of the couples who experience habitual abortion have chromosomal abnomalities.
Even if the parents have normal chromosome, there is a risk of fetal chromosomal abnormality if the mother is over the age of 35.


About 15-25% of miscarriages are caused by uterine deformity and uterine synechiae (formation of intrauterine adhesions) Infections.


Viruses such as TORCH (Toxoplasmosis, Other (syphilis, etc.), Rubella, Cytomegalovirus (CMV), and Herpes infections) can cause fetal anomaly. as Also, chlamydia, urea plasma and other bacteria can cause recurrent miscarriages. Antibiotic or anti-viral drug treatment may be necessaryin such cases.

Endocrinologic factors

In cases with abnormal secretion of progesterone lutteal phase defect can occur. In addition, other systemic endocrinologic disorders such as diabetes and thyroid diseases may also cause habitual abortion.

Immunological factors

Immunological factors are known to be the cause of approximately 50% of all miscarriages. Related conditions may be diagnosed by detecting auto antibodies that can potentially cause miscarriages and cells and cytokines involved in isoimmunity.

Unknown factors

Most cases of habitual abortions caused by an unknown factor are linked with immunological factors.
Accordingly, treatment is provided based on immunological factors.