In cases with abnormal secretion of progesterone lutteal phase defect can occur. In addition, other systemic endocrinologic disorders such as diabetes and thyroid diseases may also cause habitual abortion.
Immunological factors are known to be the cause of approximately 50% of all miscarriages. Related conditions may be diagnosed by detecting auto antibodies that can potentially cause miscarriages and cells and cytokines involved in isoimmunity.
Most cases of habitual abortions caused by an unknown factor are linked with immunological factors.
Accordingly, treatment is provided based on immunological factors.